Sentence examples for modulate cellular response from inspiring English sources

Four major approaches are currently being explored in preclinical models, some also in patients: combination with agents that modulate cellular response and disposition of oxazaphosphorines; antisense oligonucleotides directed against specific target genes; introduction of an activating gene (CYP3A4) into tumor tissue; and modification of dosing regimens.

BRCA1 expression can modulate cellular response to chemotherapy.

Polyamines interact with signaling pathways to modulate cellular response.

Finally, matrix macromolecules modulate cellular response to cytokines (i.e. the nature of the macromolecular matrix to which the cells are adherent determines cellular response to cytokines) [ 11, 13].

The presence of unreacted epoxy rings within the copolymer structure allows for the incorporation of biomolecules which could modulate cellular response on the thermoresponsive substrates.

Interestingly, this effect is diminished by the presence of other leukocytes, indicating that the white blood cells communicate with each other to modulate cellular response during a haemolytic infection.

Previous studies reported that surface topography and substrate rigidity provide biomechanical cues to modulate cellular responses such as alignment, migration and differentiation.

The induction of intraperitoneal abscesses by other zwitterionic polysaccharides is based on their ability to directly activate T-cells, which in turn modulate cellular responses at the infection site [14], [28].

These findings suggest the presence of significant differences between EPOR-mediated signaling in hematopoietic cells compared to tumor cells and that the level of EPOR expression in tumor cells may modulate cellular responses to exogenous EPO.

We suggest that MAP4K3 has two independent functions during wing development, one related to the activation of the JNK pathway in response to stress and other in the assembling or activation of the TORC1 complex, being critical to modulate cellular responses to changes in nutrient availability.

ROS are important signaling molecules that modulate cellular responses.