Sentence examples for modulate cellular proliferation from inspiring English sources

Indeed, the family of IGFBPs is known to modulate cellular proliferation or apoptosis by both IGF-dependent and -independent mechanisms.

Moreover, although regulation of Wnt signaling may be tissue specific, the signaling pathway has been shown to modulate cellular proliferation or differentiation.

Ligand occupancy of EGFR activates the RAS/RAF/MAPK, STAT and PI3K/Akt signalling pathways, which together modulate cellular proliferation, adhesion, angiogenesis and migration [ 1, 2].

It is possible that the THF-diols and LTX-diols modulate cellular proliferation by controlling the synthesis of these linoleic acid metabolites and/or by mimicking these compounds as mitogenic agents.

Next to the promotion of carcinogenesis, GGT seems to induce mutagenesis, modulate cellular proliferation and apoptotic balance by its redox-sensitive function (Dominici et al, 1999; Pompella et al, 2007; Corti et al, 2009).

Although the mechanistic pathways are not well established, the primary mechanism appears to involve suppression of COX-2-PGE2 signaling, which can modulate cellular proliferation, survival and migration, and impair tumor immunosurveillance through multiple signaling pathways [ 3].

IGFBP-3 modulates cellular proliferation with dual actions that either enhance IGFs or inhibit their actions.

Therefore, oscillatory activity of carnitine O-acetyltransferase may mediate prechondrogenic condensation by modulating cellular proliferation.

This suggests that β2M modulates cellular proliferation as well as tumour cell migration and invasion.

In conclusion, our results indicate that IFN-α regulates the activity of the MEK/ERK pathway and consequently modulates cellular proliferation through a Ras / Raf -independent mechanism.

Particularly, the expression and function of 5HTR2A in canine osteosarcoma has not yet been studied, thus we sought to determine if this indoleamine modulates cellular proliferation in vitro.