Sentence examples for modulate cellular differentiation from inspiring English sources
Thus, we utilized heparin-based microparticles to modulate cellular differentiation via protein sequestration in an in vitro model system of endochondral ossification.
In a nongenomic manner, E2 also interacts with a number of proteins that include endothelial nitric oxide synthase (eNOS) and MAPK, altering the signals that modulate cellular differentiation, migration and survival [102], [103], [104].
In this context, our identification of altered BMP4 expression is intriguing in light of a recent report showing that BMP2 and BMP4 can induce cytoskeletal changes that modulate cellular differentiation via alterations of cell morphology [ 71].
PACAP exerts neurotrophic and neuroprotective effects and modulates cellular differentiation and survival [12].
It targets abnormal desquamation of the skin, modulates cellular differentiation, and possesses anti-inflammatory properties (Leyden 2001).
Jund expression and JunD protein-protein interactions modulate tumor angiogenesis, cellular differentiation, proliferation, and apoptosis.
Moreover, although regulation of Wnt signaling may be tissue specific, the signaling pathway has been shown to modulate cellular proliferation or differentiation.
Deacetylases are a group of enzymes that affect various intracellular proteins, including histones, transcription factors, and molecular chaperones, which modulate gene expression, cellular differentiation, and survival [ 102].
IGF1, also known as somatomedin C, is expressed by both the mother and the fetus during pregnancy and plays a critical role in modulating cellular proliferation, differentiation, and apoptosis [ 6].
PRDM genes are a family of transcriptional regulators that modulate cellular processes such as differentiation, cell growth and apoptosis.
Here we discuss the current methods to 1) derive functional SMC from iPSC, 2) model vascular diseases using SMC generated from patient-derived iPSC, and 3) modulate microenvironmental cues to enhance cellular differentiation and functionality and better mimic the physiological environment.
