Sentence examples for modulate cell survival from inspiring English sources

Calcium-binding chaperone calreticulin is of special interest for its activities to promote folding, oligomeric assembly and quality control of proteins that modulate cell survival and differentiation.

The cell matrix relationship, characterised by adhesion interactions between membrane integrin receptors and the extracellular matrix molecules at the nanoscale, is known to modulate cell survival and growth.

The liver is a major site of synthesis of both soluble and membrane associated C4BP [11] prompting us to investigate whether C4BP could bind CD40 on epithelial cells and thereby modulate cell survival.

Another interesting finding is that SFAs only modulate cell survival and proliferation in response to low dose of adriamycin, which might reflect the in vivo condition, where the nutrients SFAs modulate cell response to modest DNA damage generated by endogenous factors such as ROS.

Together, these results suggest that Bmi1 can act through Myc-Lef1 and/or Bcl2 family of survival genes to modulate cell survival.

DRAM-3 may have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival.

mTOR operates in two distinct multi-protein complexes: mTORC1 and mTORC2; sharing mTOR kinase as a common catalytic subunit, mTORC1 controls cell growth and mTORC2 modulates cell survival and drug resistance.

Mir-21 limits the production of cytokines and the expression of endothelial adhesion molecules and modulates cell survival.

Because activation of these pathways modulates cell survival and chemoresistance, it is conceivable that activation of these pathways contributes to TRAIL resistance.

For instance, S100B secreted by astrocytes activates the PI3K/AKT and NF-κB pathways via the engagement of RAGE, modulating cell survival [14].

Altered EDN1 signalling is involved in carcinogenesis by modulating cell survival and promoting invasiveness [ 46].