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It is known that nanoparticles (NPs) can modulate cell fate, induce or prevent mutations, initiate cell cell communication, and modulate cell structure [7, 8].
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A microgravity environment may influence the oscillating behavior of the nucleus [ 22] and then trigger a series of mechanical adjustments that may modulate cell shape and structures, as well as functions by way of transcription activities.
The downregulation of the extracellular matrix proteins fibronectin and collagen and of the cytoskeletal protein tropomyosin indicated that CMYC may have a role in modulating cell adhesion and cell structure.
The overall goal of our research is to determine how tissue-specific variations in matrix structure and organization regulate and modulate cell activities.
Understanding these mechanisms will help us to determine how tissue-specific variations in matrix structure and organization regulate and modulate cell activities and contribute to developmental and disease processes.
The 3D structures of collagen, a major component of extracellular matrix, might modulate cell behavior, such as osteoblasts in bone formation.
We use the unique characteristics of small molecules to probe and selectively modulate cell motility.
In adult hearts, NRG1-ERBB4 signaling modulates cell growth, survival, sarcomere structure and the re-entry of cardiomyocytes into the cell cycle.
Four and a half LIM domain protein-2 (FHL2) is part of the focal adhesion structures modulating cell motility.
ROS can influence vascular, renal, and cardiac function and structure by modulating cell growth, contraction/dilatation, and inflammatory responses via redox-dependent signaling pathways.
First, Gal3 binds to oligosaccharide structures on cell surface or extracellular matrix proteins to modulate cell-to-cell or cell-substrate adhesion.
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