Sentence examples for modulate cell proliferation from inspiring English sources
The expression of p53 and p21 proteins is crucial to cell cycle control, and tumor suppressor genes including these can modulate cell proliferation by modulating cell cycle progression [ 13].
Contradictory findings from various cell culture systems support the view that EpCAM expression can modulate cell proliferation, differentiation and migration, but the outcome of modulation is strongly dependent on cell type and origin [ 16- 18].
Because CDK6 is essential for the regulation of cell proliferation, we evaluated whether miR-29b would modulate cell proliferation via binding to CDK6 in osteosarcoma cells.
Our interest is in lysophosphatidylinositol and the glycerophosphoinositols, which modulate cell proliferation and G-protein-dependent activities such as adenylyl cyclase and phospholipase A2.
Several gene targets of Hippo signaling have been identified in Drosophila, including cyclin E, diap1, and the microRNA bantam, which may modulate cell proliferation and survival [1],[12],[14],[28],[29].
We incorporated topographical and biochemical cues in our in vitro culture of human corneal endothelial cell line B4G12 (HCEC-B4G12) and hypothesized that manipulation of the extracellular environment can modulate cell proliferation, morphometry and phenotype.
The results show that extracellular thiol/disulfide redox state modulates cell proliferation rate and that this control interacts with growth factor signaling apparently independently of cellular glutathione.
These recent data show for the first time that PiT1, in addition to its retrovirus receptor and Na+-Pi cotransporter functions, modulates cell proliferation in vitro.
Given its role in modulating cell proliferation, it is not surprising that p16 alterations are one of the most common genetic/epigenetic alterations in cancer.
It has been studied as a PDZ antagonist in modulating cell proliferation, polarity, migration and stress response [17], [ 22], [ 26], [ 27].
The exact role of PAF in modulating cell proliferation, differentiation or transformation is unclear.
