Sentence examples for modulate cell cycle from inspiring English sources
PRKDC, PARP1, NPM1 and XRCC6 are hepatocellular carcinoma over-expression genes which modulate cell cycle regulation network through the modulation of UBC[ 49].
Several small molecules that modulate cell cycle control and apoptosis have been approved recently and many will be approved in the near future.
The GenMAPP analysis by pathways revealed that felodpine can modulate cell cycle, DNA replication and cell adhesion (Figure 7), thereby supporting mechanisms by which felodipine could control cell proliferation and viability.
The change in the nuclear redox environment induced by DEM could activate a shift in the activity of transcription factors that modulate cell cycle as we have demonstrated here with the decreased expression of Id2 in DEM treated cells.
One of the most important signaling cascades that modulate cell cycle progression and cell survival in many cell types is PTEN/PI3K/AKT which is deregulated in several different kinds cancers [1], [2].
Although machinery interplays in these processes still remain to be elucidated in detail, our data suggest that MS4a4B may modulate cell cycle transition by upregulation of cell cycle inhibitors and down-regulation of cell cycle activators possibly through the Ca2+/CaM signaling pathway.
Next, we examined whether knockdown of MBP-1 modulates cell cycle progression in HFF-MBPsi-4 by FACS analysis.
The goal of the present study was to investigate the role of SCD1 in modulating cell cycle progression.
In the present work, we provide new evidence that SCD1 controls the rate of cancer cell mitogenesis by modulating cell cycle progression.
Further differentiating these modes of intervention, RNA and protein expression studies show that ganetespib additionally modulates cell cycle regulatory proteins, while P6 does not.
It was proposed that µ-calpain cleaves CDKN2D after the R25, H29, Q47, G64, L113 and A127 residues, and plays an important role in modulating cell cycle regulatory protein turnover [27].
