Sentence examples for modulate cancer cell from inspiring English sources

Zhang, K. et al. LncRNA FLVCR1-AS1 asts as miR-513c sponge to modulate cancer cell proliferation, migration, and invasion in hepatocellular carcinoma.

At later stages, during cancer growth and progression, additional epigenetic changes triggered by interaction with the microenvironment modulate cancer cell phenotypes and properties, and shape tumor architecture.

Because integrin-mediated interactions with fibronectin are implicated to modulate cancer cell invasion, here we tested the hypothesis that fibronectin regulates MMP-2 activation through a Src- and NFκB-dependent signal.

To systematically identify genes that modulate cancer cell survival under stresses, we performed genome-wide shRNA screens under hypoxia or lactic acidosis.

Hence, the expression of meprinβ in cancer coupled to perturbed protein sorting and high E-cadherin processing efficiency indicate that this protease can modulate cancer cell functions.

Systems-level modeling of this complex dataset using singular value decomposition revealed that normal tissue fibroblasts variably express at least two functionally distinct activities, one which reflects transcriptional programs associated with activated mesenchymal cells, that act either coordinately or at cross-purposes to modulate cancer cell proliferation.

Linoleic acid (LA) is the most abundant polyunsaturated fat in the western diet, but the mechanism(s) by fatty acids such as LA modulate cancer cells is unclear.

Here we show that the NAD salvage pathway modulates cancer cell survival through the rarely mutated tumour suppressor p73.

In addition, these compounds, especially pyridyl-thiazoles compounds, regulated immune factors such as interleukin 10 and tumor necrosis factor, possible by directing immune system in favor of modulating cancer cell proliferation.

These findings provide a basis for more mechanistic studies that may further advance our understanding of how ECM modulates cancer cell invasion and how to ultimately interfere with this process.

Recent studies suggest a function of microtubule-interacting proteins in modulating cancer cell sensitivity to microtubule-targeting drugs, although the precise molecular mechanisms remain elusive (Mohan et al., 2013; Rouzier et al., 2005; Sun et al., 2012; Veitia et al., 2000; Wagner et al., 2005; Wang et al., 2009).