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Obviously, other proteins that are required to modulate calcium mobilization upon cellular stimulation are directed to MAMs.
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Because colchicine is very effective in inhibiting a variety of MSU-induced neutrophil effector functions, some of which are modulated by MICL, including calcium mobilization and tyrosine phosphorylation, the effect of this anti-inflammatory drug on the MSU-induced internalization of MICL was examined.
Next possibility is the H+/K+-ATPase blockade may modify ongoing intracellular events, such as calcium influx and calcium mobilization, and modulate TCTP release.
Therefore, calcium mobilization assay is commonly applied to understand how unknown small molecule ligands of 5-HT2C receptor modulate cellular signal transductions.
Calcium mobilization was measured by fluorescence.
It potently inhibited CXCL12-induced calcium mobilization and cell migration.
MFEOAz it seems inhibited the calcium influx via voltage-operated calcium channels and receptor-operated calcium channels, as well as inhibition of calcium mobilization from intracellular stores.
The compounds were subjected to assessment of their potential activities through calcium mobilization assays.
Secondary anilines, in general, outperformed tertiary analogs in inhibition of C5a-induced calcium mobilization.
Effects on PMNs were tested with transwell migration, calcium mobilization, and surface expression of CD11b.
ANG II receptors were also present as shown by ANG II-induced calcium mobilization.
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