Sentence examples for modulate apoptotic processes from inspiring English sources
Several substances that modulate apoptotic processes have been used in order to protect the hepatic parenchyma.
Several calcium sensing proteins such as calmodulin, S-100, calcineurin and calpain have been shown to modulate apoptotic processes [20,21].
Among the oncogenes, which may modulate the apoptotic process, Kit/Stem Cell Factor has a peculiar interest, since Kit is expressed in germ cells to some extent and Leydig cells, whereas SCF is expressed in Sertoli cells.
Another study suggested that melatonin may modulate the apoptotic process in the small intestine of mice exposed to 2.5 Gy gamma irradiation [ 60].
Based on this initial report, the aim of the present study was to further characterise the pathways modulating the apoptotic process in activated human HSCs.
For example, the finding that loss of Cdk5 causes frank neurodegeneration with tissue atrophy even in the absence of any detectable effect on apoptosis raises the question of whether treatments aimed at modulating the apoptotic process will be effective in modifying disease course.
Coping with defensive systems of host organisms as growth environments, intracellular bacteria, such as Shigella and Legionella, are thought to have developed a variety of strategies for modulating the apoptotic process in host cells, especially during early stages of the life cycle [ 7].
It should be stressed that many of the metabolic, stress response and apoptotic processes modulated by bile acids in mammals are essential for healthy aging and longevity regulation.
DrotAA also binds directly to specific receptors on endothelial and inflammatory cells, thereby modulating and downregulating inflammatory and apoptotic processes [ 2].
Apoptosis-inducing Factor (AIF) or Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH), for example, can translocate from mitochondria to the nucleus, where they modulate apoptotic death pathways.
JNK plays an important role in apoptotic processes [26] [28].
