Heteroatom-doped CDs can modulate compositions and structures of CDs to enhance the optical and electronic properties [42, 43].
Lipid molecules are able to selectively interact with specific sites on integral membrane proteins, and modulate their structure and function.
What's more is that the rapid development of the modern nanotechnolgy has supplied flexible methods to modulate the morphology and structure of silica, which could be adopted for the preparation of the SiO2-based nanocomposite [15, 16].
Some cosmetic compounds act on the SC, and modulate its structure and the functions that it serves.
Despite the use of cholinergic therapies in Alzheimer's disease and the development of cholinergic strategies for schizophrenia, relatively little is known about how the system modulates the connectivity and structure of large-scale brain networks.
Thus, not only does leptin induce changes in neuropeptide synthesis and secretion (9), but it also modulates the development and structure of neuronal circuits involved in metabolic control.
Methylation and acetylation of specific sites modulate chromatin structure and intensity of gene and protein expression levels, and subsequently, they regulate cellular pathways involved in cell cycle control and apoptosis.
Both PTMs have known genomic associations, H3K79me2 is found in actively transcribed genes and H4K20me3 is enriched in heterochromatin, but little is known about how and if they modulate chromatin structure and function.
Taken together, these results suggest that FMRP repression of synaptic HSPG co-receptors normally regulates trans-synaptic signaling to modulate synaptic structure and function, and that disruption of this mechanism is causal in synaptogenesis defects in the Drosophila disease model of fragile X syndrome.
Histone monoubiquitination together with other types of posttranslational modifications can modulate nucleosome/chromatin structure and DNA accessibility and thus regulate diverse DNA-dependent processes [ 28– 328.
