Mesenchymal stromal cells (MSCs) can modulate inflammation and contribute to tissue regeneration and, thus, have emerged as a promising option for cell-based therapy.
How does ErbB2 modulate signaling and contribute to transformation?
Copy-number variants (CNVs) reshape gene structure, modulate gene expression, and contribute to significant phenotypic variation.
Thus, mitochondrial DAMPs can modulate immune responses and contribute to the development of inflammatory diseases.
Finally, other dietary factors, lifestyle, and environmental factors may modulate these associations and contribute to the different results observed.
Nevertheless, some age-regulated genes identified in this analysis are known to modulate inflammatory processes and contribute to cellular proliferation.
Uncoupled mitochondrial respiration and oxidative stress in the liver further modulate lipid metabolism and contribute to the onset of hepatic insulin resistance, exacerbating hepatic steatosis with age.
Previous studies in human PCa cell lines and mice models have suggested that inactivation of PTEN and PI3K/AKT activation can modulate AR activity and contribute to CRPC [ 16- 18].
Such pathways can be modulated by HIV and contribute to the regulation of cell susceptibility to infection.
