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In addition, we also explored the extent to which Tat and opiate-induced changes in [Ca2+]i modulate activation of the NF-κB pathway.
KIRs and ILTs modulate activation of other immune receptors [ 33, 34].
Dissociated G-protein subunits, in turn, modulate activation of their downstream effectors.
Little is known about proteins that interact with PKCθ and regulate its function in T lymphocytes and thereby modulate activation of this immune cell subset.
The factors in blood that modulate activation of TGF-β1 remain obscure, but the link with LDL-cholesterol opens up a novel atherogenic pathway that requires further study.
We hypothesised that the differential VEGF-A isoform-specific regulation of cytosolic calcium ion flux could modulate activation of endothelial NFATc2.
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In addition, myostatin modulates activation of AMP-activated protein kinase (AMPK) in muscle (59), the key enzyme in a second pathway that plays a role in both muscle metabolism and growth (26, 29).
Proanthocyanidin modulates activation of LXRs [ 9], which are oxysterol-activated nuclear receptors that control cholesterol homeostasis by modifying expression of genes involved in cholesterol absorption and efflux from peripheral tissues.
Paroxetine dose-dependently modulates activation of the entire motor pathway in a way that favors motor output.
Recent evidence suggest that 1,25(OH)2D3 may affect T-dependent responses in cattle; however, mechanisms by which this vitamin modulates activation of bovine T cells are unclear.
On the other hand, the recessive resistance gene xa5 is an allele of the general transcription factors TFIIAγ (Iyer and McCouch 2004), which probably confer resistance by modulating activation of other TALE targets.
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