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It is well documented that celastrol can modulate a variety of signaling pathways.
These processes modulate a variety of mitochondrial functions, allowing living cells to respond properly to frequently changing environmental conditions.
Although low levels of ROS modulate a variety of cellular functions such as cell proliferation, high concentrations of ROS cause cell damage or apoptosis (Park et al. 2008).
These machines have specifically evolved to deliver bacterial effector proteins into host cells with the capacity to modulate a variety of cellular functions.
The inhibitors of ENTs modulate a variety of physiological processes by changing the extracellular adenosine concentrations and ENT inhibitors have a well-established role in the treatment of many diseases including cancer, HIV, and cardiovascular diseases (King et al., 2006; Jordheim et al., 2013).
Biologicals are large molecule drugs that modulate a variety of cellular and immunological functions.
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Taurine modulates a variety of cellular functions, including antioxidation, modulation of ion movement, osmoregulation, modulation of neurotransmitters and conjugation of bile acids etc. (Huxtable 1992; Satoh 1998; Schaffer et al. 2000; Sjovall 1959).
Polymer nanofiber scaffolds can be designed in a way that predictably modulates a variety of important cell behaviors towards a desired overall function.
KCNE2 encodes a single transmembrane domain protein that modulates a variety of K+channel functions in several tissues.
By affecting protein prenylation, statin modulates a variety of signalling molecules; many of which are involved in regulating adhesion (reviewed in: [28]).
In the first pathway, NO stimulates soluble guanylyl cyclase (sGC) to increase cyclic guanosine monophosphate (cGMP), which in turn modulates a variety of downstream signaling targets [4].
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