Among these, CCND1 is a cell cycle regulatory factor that modulates a critical step in cell cycle control.
A series of experiments will be described that illustrate sensory control of stepping and standing after a spinal cord injury and the necessity for the "physiological state" of the spinal circuitry to be modulated within a critical window of excitability for this control to be manifested.
Thus Gab1 plays an essential role in bringing together a multi-protein signaling complex in response to EGF that modulates a critical aspect of cellular survival.
Moreover, ZEB2 has been shown to modulate Wnt signaling, a critical pathway for the development of the genital tract [31].
5-hydroxytryptamin is mainly synthesized in the raphe nuclei and modulates as a critical neurotransmitter for different functions like wake-sleep-rhythm, behavioural arousal, and attention [17].
FOXO3 (or FOXO3a) is a member of the forkhead box class O (FOXO) transcription factors which have been shown to play critical roles in modulating a number of cellular processes, such as metabolism, differentiation, and transformation in animal cells [1] [7].
Since their discovery, these small and ubiquitous RNAs have been shown to play critical roles in modulating a wide range of physiological and pathological events [ 6].
The ability of probiotics to survive through the intestine and to modulate gut microbiota is a critical factor in determining their potential for health-related outcomes.
Golli proteins can modulate Ca2+ levels during a critical phase of oligodendrocyte development through an action on rates of cell migration and process extension and retraction, presumably post-mitotic events (Paez et al., 2007).
Distinct complement-triggered pathways have been shown to modulate critical responses that promote tissue reprogramming, pattern formation, and regeneration across phylogenesis.
