Sentence examples for modular proteins that from inspiring English sources
TALEs are modular proteins that can be strung together in a customized way to bind any DNA sequence.
The sarcomeric cytoskeleton is a network of modular proteins that integrate mechanical and signaling roles.
Nonribosomal peptide synthetases (NRPSs) are modular proteins that produce peptide antibiotics and siderophores.
Consensus-designed tetratricopeptide repeat proteins are highly stable, modular proteins that are strikingly amenable to rational engineering.
Moreover, these activities are often found within modular proteins that may contain multiple domains with differing catalytic and substrate binding properties, separated by non-catalytic linker domains.
ZFN are modular proteins that can be engineered to recognize new DNA sequences.
These results clearly establish CAR as a xenobiotic responsive modular protein that can be activated/deactivated by binding with agonistic and antagonistic ligands, respectively.
Like most of the NRs, the GR is a modular protein that is organized into three major domains: a poorly conserved N-terminal ligand-independent activation function-1 domain (AF-1), a highly conserved central DNA-binding domain (DBD) that recognizes specific GREs in target promoters -plus a dimerization region-, and a C-terminal ligand-binding domain (LBD) [10], [11].
For example, the Veli proteins are known to be part of ternary protein complexes also composed of CASK, a membrane-associated guanylate kinase that contains one PDZ domain, and Mint1, a modular protein that contains two PDZ domains (24, 25).
CBP is a modular protein that contains a number of structured domains, as well as long stretches that are intrinsically disordered and represent linker regions or interaction motifs that fold only upon binding their biological targets.
Many of these metabolites are produced by nonribosomal peptide synthetases (NRPSs), which are often large, multi-modular proteins that produce short peptides frequently incorporating non-standard amino acids.
