Sentence examples for modular labeling with from inspiring English sources
Modular labeling with distinct fluorogens allows for quantitative labeling of endocytosed and surface receptor pools.
The large number of available haptens with specific cognate proteins provides a highly modular labeling scheme, potentially limited only by the number of resolvable detection channels.
We use the radio-labeled small molecule, 18F-BODIPY-azide to label site-specifically different targeted peptides, based on a standard modular labeling protocol.
The Modular label is one source, offering the Presets and current Guide favourites Cut Copy, but now we have Midnight Juggernauts.
In addition to providing a mechanism for intracellular trapping, this enamide strategy transcends the limitations of many in vitro imaging strategies, as its modular design makes it suitable for labeling with magnetic resonance imaging contrast agents or radioisotopes for positron emission tomography.
This work opens the door for two-photon imaging with chemical tags and further illustrates how the modular organic label of chemical tags can be harnessed for state-of-the-art biological imaging.
Although no prior knowledge was used for guiding community identification, interestingly we found these communities can be labelled with discernible biological processes, highly indicative of functional modular design.
It is our hope that this modular methodology will aid in both the expansion of the comparative study of antibodies labeled with different radionuclides and the development of novel antibody-based radiopharmaceuticals. Since more and more antibodies and dienophiles are being developed, this modular approach will likely lead to the rapid development of many novel imaging agents.
The main goal of this study was to demonstrate the synthetic feasibility of a triazine-based modular platform, in which the spacer core molecule could be conveniently linked to targeting groups (multimeric or monomeric) and bifunctional chelator labeled with radiometal using either "click chemistry" or standard amidation reactions from an activated NHS ester.
The dendrimeric formulations were labeled with 95% labeling efficiency.
