Exact(2)
In this work, we improve GlcNAc production through modular engineering of B. subtilis.
The modular engineering of metabolic pathways, demonstrated in this work, will expedite the design and development of robust and efficient microbial cell factory for the production of various value-added chemicals from diverse cost-effective feedstock in nature.
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An adequate support system for modular engineering would increase reuse of variable parts of the machine or plant and, by that, enhance the engineering efficiency.
Modular engineering enables the construction of chimeric polypeptides in which selected domains, potentially from different origins, provide the required activities.
This study presents the use of a modular engineering process model, informed through literature, to evaluate the nitrogen and phosphorus resource demand of five microalgae to biofuels production systems.
"It's good modular engineering," Mr. Straubel said.
This work significantly enhanced GlcNAc production through modular pathway engineering of B. subtilis, and the engineering strategies used herein may be useful for the construction of versatile B. subtilis cell factories for the production of other industrially important chemicals.
Collectively, modular pathway engineering of metabolic network can be an effective approach in strain development for optimal biofuel production with cost-effective fermentable sugars.
Moreover, owing to the modular design, sophisticated engineering of diverse domain components becomes possible.
This book highlights the recent advances in nanotheranostics from basic research to potential applications, and discusses the modular design and engineering of multiplex nanoparticles including gold nanostructures, luminescent nanoparticles, dendrimers and liposomes.
The engineering of modular PKSs could open access to the deliberate production of both existing and novel compounds.
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