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Here, a stepwise modular engineering approach was introduced to systematically identify and eliminate metabolic pathway bottlenecks.
Furthermore, we optimized the pathway by a modular engineering approach and deleting genes involved in the regulatory and competing pathways.
Here, we report a modular engineering approach that systematically removed metabolic pathway bottlenecks and led to significant titer improvements in a multi-gene fumarate metabolic pathway.
A repebody specifically binding to human TNF-α (hTNF-α) was selected through a phage display, and its binding affinity was increased up to 49 nM using a modular engineering approach.
In a modular engineering approach, yeast cells were co-transformed with a S. cerevisiae GGPP synthase (ScGGPPS) [ 29] and SsLPPS alone, or in combination with SsSS or SsdiTPS3.
Similar(54)
A modular tissue engineering approach may have advantages over current therapies in providing rapid and sustained revascularization of ischemic tissue.
Using an engineering approach, the input/output function of each modular element is characterized independently, providing a toolkit of elements that can be linked in different ways to provide various circuit topologies.
This is the engineering approach".
"It's good modular engineering," Mr. Straubel said.
"Her approach is almost like an engineering approach".
The software engineering approach was iterative.
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