Sentence examples for modular domain can from inspiring English sources
Due to its independently folding nature, a modular domain can often be successfully used as a tool in proteomic research.
Between these two regions, a variable number of potential protein protein interaction modular domains can be found.
Both of these examples show that simple modular domain recombination can generate functional synthetic protein switches to rewire cell signalling and how a modular framework can facilitate the engineering of such protein switches.
This shows that the Hedge domain can also evolve in a modular fashion and separate from the Hog domain.
The DNA-binding domain can be customised to recognise virtually any sequence using a modular recognition code that is bound by TALE proteins, a group of naturally occurring proteins found in plant bacteria (Boch et al., 2009).
With the low sample requirement and short assay runtime, SH2-PLA can provide a useful platform on which to develop high throughput modular domain binding assays applicable in both basic and translational cancer research.
Since the HKs in TCS systems have a modular structure comprising two conserved domains (the sensor and transmitter domains), we can hypothesize that the HK sensor domain can be swapped between different signalling proteins so that the downstream network of a signalling pathway can respond to a non-native input signal.
Each subunit shares a modular domain architecture: an amino terminal domain (ATD) followed by a ligand-binding domain (LBD), a transmembrane domain and a carboxyl terminal domain.
The four mammalian Notch receptors (Notch1-4) all have a similar modular domain organization.
The proteins nhr_67 and ESR1 contain the PF00105 domain, whereas daf-21 and HSP90AA1 contain the modular domain (PF02518, PF00183).
Our adherence towards modular domain definitions ensured sequence continuity for individual domains; unless additional inserted domains also were present (except for composite domains described later in this section).
