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Strategies to develop less immunogenic vectors have focused on modifying the naturally occurring proteins in the viral coat [ 71].
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Our approach was to modify the naturally occurring and synthetically challenging antibiotic thiolactomycin (TLM) to the more tractable 2-aminothiazole-4-carboxylate scaffold to generate compounds that mimic TLM's novel mode of action.
The drug works by modifying the way cholesterol levels are naturally controlled.
By modifying these naturally occurring proteins, Lu hopes to make them more efficient at killing microbes, and potentially to develop them for use against infection in humans.
They had agreed to bid naturally on the second round, modifying the convention, and landed in three hearts.
Second, we discuss therapeutic benefits that may be derived from the ability to modify the behavior of naturally occurring nanomachines, using as an example the concept of delaying DSB repair in rapidly dividing cancer cells to increase their natural sensitivity to radiation therapy.
He naturally modified the slogan, replacing Orthodoxy with Marxism and autocracy with the leader's iron rule.
Note that we naturally modify the decoding algorithm from [30] to perform erasure correction in a cooperative manner.
In this report we present data for a novel HIV-1 entry inhibitor, grifonin-1 (GRFN-1), that was obtained by modifying and truncating the naturally occurring lectin, griffithsin.
Naturally, we can modify the multivariate Baskakov operator as multivariate Baskakov-Durrmeyer operator (110).
To achieve much better performance when the mutual coherence is not optimal, one would naturally try to modify the measurement process to achieve a better global incoherence.
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CEO of Professional Science Editing for Scientists @ prosciediting.com