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We previously showed that activation of the cAMP-PKA signal potentiates SF-1 transactivation by modifying the interactions between SF-1 and its cofactors, and PKA-induced activation of ArPII requires SF-1 (Fan et al. 2004).
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The results presented in this study underscore the importance of dissolved metals in modifying the interaction between the adsorbate and the pyrite surface.
The effect of foundation settlement on the bridge vehicle interaction (BVI) is investigated by modifying the interaction forces due to the deformed shape of deck.
The performance of this computationally expensive problem is improved by modifying the interaction potential due to nearby particle moves, instead of fully recalculating it.
We hypothesize that EFAL species could migrate to the CZA catalyst during DME synthesis through a water-assisted mechanism, modifying the interaction between Cu and ZnOx at the Cu ZnOx interface where the active copper sites are likely located.
This R55K K225R double mutation may either severely disrupt the function of the active site by modifying the interaction between the substrates, or cause protein misfolding.
The PPARG Pro12Ala amino acid substitution abolishes the alcohol-specific regulation of PPARG presumably by modifying the interaction with the cofactor PGC-1α.
The effect of INH is captured by modifying the interaction of its known target, NADH-dependent enoyl-[acyl-carrier-protein] reductase, inhA (Rv1484) [ 45].
Methylation does not interfere only in transcription factor binding activity, but also modulates chromatin structure by modifying the interaction between core histones and DNA.
Testosterone may interfere with the effects of cholinesterase inhibitors by decreasing the amount of drug that reaches the brain or by modifying the interaction of the cholinesterase inhibitor with cholinesterase [ 103, 104].
48– 50 For rs4532, located in the 5′ untranslated region of DRD1 gene, the variant modulates the expression and stability of mRNA and influences DRD1 gene expression by modifying the interaction between DNA binding domain and the regulatory elements.
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