Sentence examples for modifying the functions of from inspiring English sources

Lysosomal proteases are also involved in the degradation of proteins not only to inactivate proteins but also for modifying the functions of some proteins [39].

Proteolysis is a cellular mechanism not only for maintaining the concentration of proteins but also for regulating or modifying the functions of proteins [33], [34].

17 NE is a neurotransmitter; it spills over into the systemic circulation, further modifying the functions of the liver, adrenal cortex, pancreas, and kidneys.

A less likely possibility is that LPA might act indirectly by modifying the function of a PPARγ coactivator.

Phosphorylation by Cdks directs the cell cycle by modifying the function of regulators of key processes such as DNA replication and mitotic progression.

Unlike the dominant effect of germline p53 mutation on cancer risk, germline p53 polymorphisms exert more subtle effects on tumor onset or risk of cancer by modifying the function of p53.

However, ubiquitin also has important roles in modifying the function of individual proteins required for specific processes, e.g. ubiquitination of PCNA (proliferating cell nuclear antigen) is required for bypass of replication blocking lesions in DNA [6], [7], [8].

These moieties are also capable of reacting with thiol groups by Michael addition, thereby modifying the function of target proteins.

Fixation of the stapes footplate decreases its ability to vibrate, thereby significantly modifying the function of the normal ossicular chain, and always leads to conductive hearing loss (Dubreuil et al. 1994; Häusler 2004; Møller 2007).

In addition, vitamin D seems capable of modifying the function of cells classically associated with adaptive immunity whereby activation of VDR downregulates autoimmunity by promoting the differentiation of T-cells into regulatory T-cells [ 12].

Memantine, a drug commonly used to treat Alzheimer's disease, is another potential FXS therapy aimed at modifying the function of FMRP targets and rectifying the gamma-aminobutyric acid (GABA)/glutamate imbalance by modifying ionotropic glutamate receptor activity.