Your English writing platform
Discover LudwigSuggestions(1)
Exact(1)
Thus, in the late onset of a disease such as cancer, mtDNA polymorphisms can potentially play a role in modifying the cancer risk.
Similar(59)
By E. B. White The New Yorker, April 2 , 1960P. 95 The pharmaceutical industry wants Congress to modify the cancer clause in the pending color-additives bill--a clause prohibiting the use of carcinogens in food, drugs, & cosmetics.
The pharmaceutical industry wants Congress to modify the cancer clause in the pending color-additives bill--a clause prohibiting the use of carcinogens in food, drugs, & cosmetics.
Variation in the penetrance estimates for BRCA1 and BRCA2 mutations carriers suggests that other genetic polymorphisms may modify the cancer risk in carriers.
According to the definition of Boland et al (1998), if at least two of these five loci were modified the cancer was considered as unstable.
However, this classification error is unlikely to be substantial in view of the low use level, which is unlikely to modify the cancer risk.
Identifying racial differences in genetic or lifestyle factors, which may modify the cancer risk of BRCA1/2 mutations, is also a priority for future research.
However, penetrance estimates vary and several lines of evidence indicate that other genetic and environmental factors modify the cancer risks conferred by these mutations [ 15- 17].
Because these two genes are involved in metabolic activation via O-acetylation [ 184– 187], their genetic polymorphisms could modify the cancer susceptibility related to carcinogen exposure.
Such evidence suggests that genetic or other risk factors that cluster in families modify the cancer risks conferred by BRCA1 and BRCA2 mutations.
Another possibility is that this composite genotype in combination with certain genetic background and/or environmental factors, could modify the cancer risk by increasing genetic inestability or by altering the effect of the normal DNA damage response.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com