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What works — like modifying the bacterial proteins to which antibiotics would otherwise bind — wins.
Background: The magnetosome biosynthesis is a genetically controlled process but the physical properties of the magnetosomes can be slightly tuned by modifying the bacterial growth conditions.
The targeting constructs (pBDT and pBDU) were generated by modifying the bacterial artificial chromosome (BAC) clone (RP23-324O18 derived from C57BL/6J) using recombineering method with the plasmids, pRedET (Gene Bridges GmbH, Heidelberg Germany) [ 31].
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Interestingly, litter diversity modified the bacterial community structure, while plant richness altered the total bacteria and denitrifier abundances as well as DEA.
These results suggest that polarity of the solvent environment can be manipulated as a design parameter to control or modify the bacterial adhesion process.
The team then modified the bacterial genome so that the regulatory DNA responsible for activating one of these genes was attached to a gene for a protein that glows when produced.
To highlight its potential, we then survey the impact X-ray crystallography has had on advancing an understanding of a class of enzymes that modify the bacterial cell wall.
However, using host NOD2 deletion or by modifying the structure of bacterial PGN, we show that a defective NOD2/PGN sensing system fosters increased opportunity for bacterial adherence/colonization of the intestine.
Our data is consistent with the hypothesis that the expression of these genes may serve to maintain the integrity of the bacterial periplasm and to provide a favorable environment for proper membrane protein folding, possibly by inducing a fine-tuned stress response and/or via modifying the composition of the bacterial cell envelope.
Lioussanne et al. [ 47] showed that direct root colonization with either G. mosseae or G. intraradices significantly modified the DGGE bacterial community structure of tomato rhizosphere.
The infected male's sperm is modified by the bacterial infection and, as a result, cannot fertilize eggs from female unless they are rescued by the same strain being present in the cytoplasm of the eggs [ 11, 12].
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