Sentence examples for modifying the activity of from inspiring English sources

Transcriptional activation of a number of IFN-inducible genes was rapid and independent of new protein synthesis, indicating that IFNs activated transcription by modifying the activity of pre-existing proteins and transcription factors.

Modified versions of these surrogates should provide agents capable of modifying the activity of these targets and enable one to study their involvement in specific biological processes as a means of target validation for downstream drug discovery.

Thus, oncogenic activation can also interdict TGFβ growth inhibitory responses by modifying the activity of downstream elements such as cell cycle inhibitors or transcriptional cofactors of Smad transcription factor activity.

They made the surprising discovery that the virus was only the indirect cause; it triggered the cancer by modifying the activity of a gene already within the cells.

Cyclopamine is thus a very useful reagent for probing and modifying the activity of the important and widely studied Hh pathway.

LncRNAs can regulate gene transcription either through directly binding to the RNA polymerase II, or modifying the activity of the transcriptional co-regulators (Mercer et al., 2009).

They participate in Ca2+ signal transduction by binding and modifying the activities of specific target proteins.

A number of Ctn2-binding partners have been identified to date which together suggest that it functions primarily through modifying the activities of its binding partners.

Such understanding would be helpful for enhancing, re-directing or modifying the activities of T cells under physiological and pathophysiological circumstances.

Moreover, green tea catechins have the ability to modify the activity of multiple intracellular molecular targets, including mitogen-activated protein kinase (MAPK), protein kinase C, and PI3K/Akt pathways.

Scientists in Finland said that between five and 10 per cent of severe violent crime in the Scandinavian country could be attributable to both sets of genes, each of which can modify the activity of the brain.