Exact(3)
This fibrinolytic system is utilized by cancer cells during metastasis and several pathogenic species of bacteria have been found to manipulate the host plasminogen system to facilitate invasion of tissues during infection by modifying the activation of this process through the binding of plasminogen at their surface.
Therefore, fructose may indirectly influence appetite and reward through changes in the levels of peripheral neural input or metabolic intermediaries modifying the activation of brain regions implicated in appetite and reward.
Changes in cellular signalling may also be involved in the establishment of senescence by modifying the activation of transcriptional programs in response to extracellular and intracellular stimuli, such as oxidative stress and a pro-inflammatory microenvironment, as well as by inducing changes in the cell physiology.
Similar(57)
Approximately 0.5% of the library (∼100 dsRNAs) modified the activation of the reporter by ΔNLRP6 in a manner validated by low throughput confirmation of the primary screen.
Anesthetics modify the activation of the central nervous system by inhibiting excitability neurons or exciting inhibitory neurons.
Thus, GABRA2 variants seem to modify the activation of reward-related areas after exposure to alcohol-associated cues.
However, in this study, CQ failed to modify the activation of Bid, indicating that the lysosome-mitochondria axis is not involved.
Due to the fundamental role of HA in determining the viscoelasticity of fluids in soft connective tissues, its alteration could therefore modify the activation of the receptors, producing non-specific musculoskeletal pain.
These DNA adducts therefore act as effective biological markers of tobacco smoke carcinogen exposure, integrating differences in metabolic capacity that modify the activation of such chemicals in the body.
Furthermore, it was shown that SLPI controls cell proliferation by regulation of growth-associated genes such as cyclin D and transforming growth factor (TGF -β1 [ 7], modifies TGF -β1ivation of macrophages [ 4] and regulates the LPS-induced activation of the transcription factor "nuclear factor kappa B" (NF-κB) [ 8, 9].
Our data further demonstrates that syndecan-1 restrains cell migration by modifying the activation state of the α2β1 integrin.
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