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Established or suspected dietary factors modifying risk of CRC are red meat, cereals, fish, and fibre.
Our analysis also indicates the need for research to evaluate the role of CPAP in modifying risk of GDM (53).
Thus, identification of additional predictive factors modifying risk of disease may have implications to genetic counseling and timing of prophylactic surgery.
Although further study is required to confirm whether genetic variation in SMAD3 plays a role in modifying risk of breast cancer, SMAD3 has been shown to interact with the BRCA2 protein - suggesting a possible mechanism through which SMAD3 may modify BRCA2 function [ 27].
However, obesity, as well as physical activity, was not shown to be interacting with sleep duration in modifying risk of CRC in our study.
Similar(55)
To investigate the effect of surgical menopause due to bilateral oophorectomy on mortality, in light of evidence that bilateral oophorectomy among premenopausal women rapidly reduces endogenous hormone levels, thereby modifying risks of cardiovascular disease and breast cancer.
Our aim was to determine whether a change in fatty liver status (either development of new fatty liver, or resolution of existing fatty liver) over five years modified risk of incident hypertension at five year follow-up.
Treatments that modify risk of death among those with diabetes may change future dementia risk.
This line of research suggests novel epigenetic mechanisms whereby diet may modify risk of human disease.
Polymorphisms in genes involved in all these processes may modify risk of developing idiosyncratic drug reactions.
CYP19A1 methylation also appeared to modify risk of early B2 associated with body weight.
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