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The mechanism of host tissue displacement may include cell wall modifying proteins like expansins that have host cell wall-specific activity.
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Based on sequence alignments with representative GenBank sequences Has-ubfm encodes an open reading frame (ORF) that shares significant similarity with ubiquitin-like fold modifying proteins from various organisms (Fig. 3A).
Very recently, the wild type α-lytic protease was shown to cleave small ubiquitin-like modifier (SUMO) modified proteins to form a GG-K remnant, thus providing a new strategy for mapping of SUMO-modified proteins without the need for introduction of mutations.
Lysyl oxidase (LOX; ExPASy ENZYME entry: EC 1.4.3.13) and members of the LOX-like family, LOXL1 LOXL4, are copper-dependent enzymes that can modify proteins of the extracellular matrix.
We find that itaconate directly modifies proteins via alkylation of cysteine residues.
The CGRP receptor is a complex consisting of the G-protein coupled calcitonin receptor-like receptor (CLR) and a single transmembrane receptor activity modifying protein (RAMP1) [12].
Blue BR (bBR) membranes contain modified proteins that exhibit an O-like resting state (bR B ; λmax ∼ 603 nm) and are produced by either mutagenesis or low pH-induced protonation of the Asp-85 residue.
In contrast, the Drosophila genome has only three collagen-like genes, and it is considered that these protein-modifying enzymes modify proteins other than collagen [ 42].
Consequently, these modified proteins cannot exert the whole set of intra- and intermolecular interaction events like their full-length counterpart.
Chemical evaluation of conformational differences in native and chemically modified proteins.
The process of carbamylation, like citrullination, is not restricted to RA but the formation of antibodies against these modified proteins is.
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