Your English writing platform
Discover LudwigSuggestions(2)
Exact(4)
This observation therefore indicates a transient and stage-specific interaction between the modifying lipid of Tγ and Tα-GDP.
On the other hand, no significant effect of Tα nor GTPγS was observed for Tγ−Tβ cross-link level in the membrane pellet (panel c, lanes 2, 4, and 6), suggesting a default position of the modifying lipid of Tγ in the Tβ pocket.
The weak signals of Tγ−X cross-link constantly observed in the membrane fraction under various conditions are suggestive of location of the modifying lipid of Tγ in equilibrium between the Tβ pocket and the lipid layer surface, when the receptor is in the resting state of signaling.
The Tγ−Rh* interaction was eliminated by GTPγS disruption of the Rh*/Tα/Tβγ ternary complex, indicating a transient interaction between Rh* and the modifying lipid of Tγ in the ternary complex.
Similar(56)
LPS modification also seems to be important for colonization of P. luminescens since mutation of pgbE1, possibly responsible for modifying lipid A moiety of LPS, lost its ability to colonize nematode infective juveniles [16].
These results suggest that directed destabilization of emulsified lipids using interfacial engineering approaches has potential for modifying lipid digestibility and/or the release of bioactive agents at specific sites within the GIT.
Phase I enzymes are involved in the first stage of detoxification of xenobiotics compounds and implicates in enzymatic transformation of a chemically modifying lipid soluble toxin into water-soluble toxin.
The accumulation of these bioactive lipid molecules as ceramides and diacylglycerols might modify lipid characteristics of the cell membrane, interfering in insulin action.
The second objective was to find out whether SP-A from the hypophase associates with DPPC/Re-LPS-mixed monolayers as well as with DPPC monolayers (13, 14) and whether SP-A modifies lipid lateral organization of such monolayers.
This nanosystem, consisting of modified lipid nanocapsules coated with a cationic polymeric shell composed of chitosan (CS), was able to allocate the hydrophobic drug PTX in the inner oily core, and to associate onto the surface the genetic material CpG.
If recruitment of each auxilin required a modified lipid molecule, the total number of such molecules would be <1% of the total in the vesicle bilayer, even to saturate the heavy chains with auxilin (probably an overestimate of the necessary occupancy).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com