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Epigenetic changes are alterations of genomic function not modifying gene structure as such.
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Relative to the P1-wr (white pericarp and red cob glumes), we show that the tandem repeats of P1-mm have a modified gene structure containing a reduced number of repeats.
Moreover, rearrangements caused by eventual ectopic recombination can modify gene structure, including toxin biosynthetic locus [ 49].
The modified gene structure was supported by the presence of similar proteins in C. neoformans var.
However, the activity of the elements near important genes can potentially modify gene expression, as well as the rearrangements caused by ectopic recombination can modify gene structure.
Some of these changes can potentially modify gene structure or expression and, thus, facilitate the emergence of new strains of this pathogen.
Proteins containing an RCC1 domain are believed to be involved in altering chromatin structure and modifying gene expression.
However, these epigenetic patterns can be altered under certain environmental conditions (inflammation, viral infections and chemical reagents), changing chromatin structure and modifying gene transcription, contributing to cell plasticity and, ultimately, determining the strength of post-transplant immune responses (Fig. 1B).
FOXM1 can be seen in indirect control of chromatin structure modifying genes in FOXM1-induced NBS1 activation of ATM [48].
The tolerance to modifications can be measured by directly modifying a gene structure or by estimating the gene variation in a population.
Attenuators are regulatory RNA structures that modify gene expression by altering transcription or translation.
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