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Signal transduction leads to modifying expression of defense-related genes and defense mechanisms against BPH, including sieve tube sealing, production of secondary metabolites, and induction of proteinase inhibitor.
Together, these expression patterns not only help to validate the ChIP-chip data, but they also reinforce a common theme, which is that Ubx is modifying expression patterns, not simply turning genes on or off throughout the entire haltere.
Unpublished data from our laboratory have shown that maize somatic embryogenesis can be altered by modifying expression of maize Hb1 and maize Hb2.
Both physiological and pathological cellular signals rapidly converge on P-TEFb regulation by modifying expression and activity of the complex to allow cells to properly respond to different stimuli.
Mouse models of human heart disease frequently involve the use of a genetic 'switch' that induces Cre recombinase activity in specific cardiac cells, thereby modifying expression of the gene under study in the living heart.
Strategies to effectively direct MSCs to sites of injury and inflammation including genetic manipulation, modifying expression of homing and adhesion receptors, and antibody or peptide-directed cell targeting [ 110] are actively being pursued.
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Functional delivery of oligonucleotides to epidermis in order to edit or modify expression of mutant genes.
The total fluorescence of mCherry-P and mCherry-U were similar in the absence of MazF, indicating that recoding the transcript did not modify expression (Fig. 1b).
The resolution of mutation coverage illustrates considerable complexity in the position and orientation of selected integrations in the vicinity of verified cancer drivers and suggests uncharacterized locus-specific mechanisms by which these mutations modify expression in a position dependent manner.
William Jeffery and his colleagues have isolated a master control gene whose modified expression leads to blindness in cave fish (Yamamoto et al. 2004).
Previous studies have shown that combination therapy modifies expression of hundreds of genes in vitro and in vivo.
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