Sentence examples for modifying enzymes to from inspiring English sources

Recruitment of histone modifying enzymes to one of these sites terminates heterochromatin spreading by generating an active chromatin conformation at the barrier.

In summary, we propose that CBF transcription factor might participate in recruiting chromatin modifying enzymes to repress MyoD early target genes by locally inducing a repressive chromatin structure.

The current data show that the daf-2 pathway acts in part through regulation of DNA/chromatin modifying enzymes to control hypoxic sensitivity.

For example, the MHC class II transactivator (CIITA) and the regulatory factor X (RFX) proteins serve as focal points for recruiting histone modifying enzymes to MHC class II promoters.

CAR in turn could regulate the exclusion of DNA methyltransferases (DNMTs) and/or recruit DNA demethylases and different histone modifying enzymes to the Cyp2b10 promoter (for a review on the role of histone modifying enzymes in nuclear receptor mediated gene regulation see Gronemeyer et al. [48]).

Among the transcription factors that have been identified within boundary complexes are Upstream Factors 1 and 2 (USF1 and USF2), which recruit histone modifying enzymes to the beta-globin barrier element [31], [32] and occupy the alpha-spectrin barrier element as well [33].

Removal of this material resulted in an approximate doubling of the specific activity of the modified enzyme, to 17%% (based on kcat/ Km values) of the activity of the wild-type enzyme (Table 1) and far-UV CD spectroscopy suggests that the modified enzyme was correctly folded as its spectrum is identical to that of the wild-type enzyme.

Inflammatory cells provide growth factors that sustain proliferation, and survival factors that allow escape from apoptosis; it also contributes to extracellular matrix (ECM) modifying enzymes, and to pro-angiogenic factors that facilitate angiogenesis, invasion and ultimately metastasis [ 3].

Many different histone modifying enzymes contribute to the dynamic regulation of chromatin structure and function, with concomitant impacts on gene transcription.

As growth occurs in compost, casing layer and fruiting bodies, genes encoding fungal cell wall modifying enzymes need to be expressed in all growth stages.

Mutations in the carboxy-terminal core sequence are often tolerated by modifying enzymes, leading to natural libraries of peptide products [ 4].