Sentence examples for modifying enzymes involved from inspiring English sources

Xist RNA is required for XCI and most likely attracts chromatin modifying enzymes involved in the silencing process [6], [7].

We identified the specific modifying enzymes involved, and uncovered a novel functional role of H2AR29me2 in gene silencing in vivo.

Hence, therapeutic proteins harbouring this modification can now be produced recombinantly without any knowledge of the modifying enzymes involved.

A cell-based phenotype screening of small molecule compounds is a very useful approach to identify modifying enzymes involved in the cellular clockwork.

Further examples are given on predictable interactions between chemicals which need bioactivation for exerting their toxicity and chemicals which effect hormonal status and other endogenous factors which in turn modify enzymes involved in the control of toxic metabolites.

Our data further suggest that the hypothesis that depletion of NO66 from these genes could be due to recruitment of Osx and chromatin modifying enzymes involving histone or factor acetylation and methylation, thus altering the chromatin from a repressed to an active state, although, the exact mechanism by which this occurs is not known.

The challenge we now face is to identify the specific chromatin-modifying enzymes involved in coupling of proline metabolism to altered reprogramming of gene expression.

Furthermore, the protein-modifying enzymes involved could differ between the two isoforms, even for sites that are identical in sequence.

Indeed, it is very likely that the protein-modifying enzymes involved could differ between isoforms, even for sites that are identical in sequence.

The histone modifying enzymes directly involved in ccRCC development are SET domain containing 2 (SETD2), a histone H3 lysine 36 methyltransferase, Jumonji/ARID domain-containing protein 1C (JaRID1C), a histone H3 lysine 4 demethylase and ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX) a histone H3 lysine 27 demethylase [ 43, 44].

Specifically, he discussed how glucose-derived acetyl-CoA can be used as a substrate to modify two enzymes involved in glucose metabolism, pyruvate kinase M2 (PKM2) and phosphoenolpyruvate carboxylase (PEPCK).