Sentence examples for modifying enzymes are from inspiring English sources
Mutations in other antibiotic modifying enzymes are known to alter regiospecificity54, and the cladinose hydroxyl of azithromycin is a possible phosphate acceptor.
As aberrant epigenetic modifications have been linked to many diseases, inhibitors of histone modifying enzymes are very much in demand.
Important classes of phospholipid modifying enzymes are phospholipid kinases, phospholipid phosphatases and phospholipases.
The precise sequences that are involved in recruitment of histone modifying enzymes are yet to be determined.
For example, histone modifying enzymes are required for the regulation of virulence traits and for pathogenesis in C. albicans [13] [23].
The field of posttranslational protein modification represents an area of increasing research interest as new protein modifying enzymes are discovered [5], [6], [7].
Nucleic acid-modifying enzymes are widely used in numerous applications.
To determine which histone-modifying enzymes are regulated during IAE pathogenesis, we next performed a PCR array for genes of chromatin modification enzymes.
New tools for discovering key histone-modifying enzymes are being developed and new tool compounds for histone acetyltransferases and other histone-modifying enzymes are emerging in the patent literature.
We discuss evolving evidence that DNA/histone modifications and chromatin-modifying enzymes are altered in immune-based diseases.
Small-molecule inhibitors of the catalytic activity of histone-modifying enzymes are of interest both as therapeutic agents, as shown by the clinically-approved histone deacetylase inhibitors Vorinostat and Romidepsin [9], and as chemical probes for investigating biological function.
