Sentence examples for modifying dna and from inspiring English sources

In addition to modifying DNA and lipids, oxidative stress promotes the formation of neoantigens through posttranslational peptide modification.

Beside these the nsSNPs perturb gene regulation by modifying DNA and transcriptional binding factors [ 6– 9] and the maintenance of the formational integrity of cells and tissues [ 10].

Furthermore, this article describes the principles and limitations of commonly used methods for the assessment of oxidatively modified DNA and DNA stability.

"Classically, DNA methylation has been viewed as one of the most permanent ways to modify DNA and alter gene expression".

There are also many distinct activities that modify DNA and chromatin structures leading to heritable epigenetic changes.

Conversely, these polymorphisms may create binding sites for co-repressors, methylated DNA-binding proteins, or other proteins involved in epigenetic silencing that modify DNA and silence gene expression.

One pair was coupled to fluorescein modified DNA and the other pair to Cy5 modified DNA as shown in Figure 4A.

At the chromatin level, epigenetic control is mediated by proteins that modify DNA and chromatin, and remodel nucleosomes.

Alkylating agents directly modify DNA and often induce bulky DNA damage that is repaired via the nucleotide excision repair pathway (NER).

Structures of the Dpo4 polymerase in complex with modified DNA and incoming dNTPs provide models for investigating the structural features that determine lesion bypass efficiency and fidelity.

Diffusible and membrane bound lipid electrophiles are known to modify DNA and protein substrates and modulate cellular pathways including ER stress, antioxidant response, DNA damage, heat shock, and apoptosis.