Sentence examples for modifying compounds from inspiring English sources

These findings underline the importance of binding loop rigidity in canonical serine protease inhibitors and the need to maintain structural stability when modifying compounds of this class.

In fact, our result shows that HAND1 promoter demethylation is insufficient to fully reactivate HAND1 expression because of enhanced engagement of PRC2, resulting in a bivalent histone methylations, which, however, is sensitive to the combination treatment of histone modifying compounds DZNep and TSA.

For these reasons, targeting the production of the aggregation prone and potentially toxic 42 amino acid residue-long variant of Aβ (Aβ42) has been subject to extensive research with the aim of developing disease modifying compounds that inhibits or modulates the enzymes responsible for the formation of Aβ (see elaborating reviews elsewhere [ 5– 7]).

Treatment of the enzyme with a variety of amino acid modifying compounds suggests that cysteine, histidine, arginine, tryptophan, and tyrosine residues are important for activity.

The obtained results confirmed the validity of the earlier described findings that the fate of modified GNPs depends on a charge which is carried by the modifying compounds and the negatively charged compounds increase the stability of nanoparticle dispersion [15].

As described above, these bivalent genes that are lowly transcribed (not completely silenced) might be most susceptible to histone modifying compounds such as DZNep/TSA as illustrated in this study, but not to DNA demethylating agents.

With its ability to synthesize, degrade, and modify compounds in the gut, the human microbiota may be serving as a modulator and modifier of environmental inputs like acrylamide affecting how these inputs interact with the genome.

As far as your concern over cancer-causing agents in mushrooms, some studies found that synthetic and chemically modified compounds, which included agaritine — a mycotoxin found in fresh mushrooms, produced carcinogenic effects in mice.

Aluminium and lanthanum modified compounds are among the most effective compounds for targeting P. Flocculants and ballast compounds can be used to sink cyanobacteria, in the short term.

High logP values of the modified compounds suggested that the lipophilicity of the steroid conjugates may have contributed to membrane permeability.

Finally, the performances of the persistent organic pollutant (POP) properties, the synthesis feasibility and the fire resistance of the modified compounds were evaluated.