Sentence examples for modifying chromatin structure from inspiring English sources

Regarding HATs, they regulate gene expression by catalyzing acetylation of the N-terminal region of histones, thereby modifying chromatin structure in a manner that facilitates transcriptional activation [18].

Others act by modifying chromatin structure.

Polycomb group (PcG) proteins repress transcription by modifying chromatin structure in target genes.

These studies suggest that heterochromatin of insects may accumulate genes important for its own establishing, maintaining, or modifying chromatin structure.

Metabolites, including those generated during ethanol metabolism, can impact disease states by binding to transcription factors and/or modifying chromatin structure, thereby altering gene expression patterns.

Histone deacetylase inhibitors (HDIs) accelerate the osteoblast differentiation process by blocking the activity of histone deacetylases (HDACs), which alter gene expression by modifying chromatin structure.

In this review, we analyze how these elements modify chromatin structure in a hierarchical manner by acting on the nuclear machinery.

The cellular response to N-activation was analysed under several conditions known to modify chromatin structure packaging.

For example, subtle genetic mutations in CBP may be amplified if a person has a specific environmental exposure to an agent that modifies chromatin structure.

Transcriptional control during the pluripotent state is applied by the polycomb group (PcG) of proteins that work to modify chromatin structure.

Core PcG genes modify chromatin structure to prevent transcriptional activation of key target genes, including the well-characterized homeotic genes that are critical for developmental patterning and cell fate determination [30].