Sentence examples for modifying chromatin organization from inspiring English sources

PcG proteins form large complexes, including PRC1 (Polycomb repressive complex 1) and PRC2 (Polycomb repressive complex 2), which silence target genes by modifying chromatin organization.

The current model for ER action suggests that the ER modulates the rate of transcription through interactions with the basal transcription machinery and by altering the recruitment of co-activators that modify chromatin organization at the promoter level of target genes [ 3- 5].

Others act by modifying chromatin structure.

SUMO is capable of binding to chromatin by modifying chromatin remodeling proteins and transcription factors [ 48].

Rhythmic recruitment of key factors that modify chromatin structure and transcriptional and translational processes leads to the circadian organization of the mammalian transcriptome.

Cho, H. et al. A human RNA polymerase II complex containing factors that modify chromatin structure.

The Kingston lab is interested in understanding the fundamental mechanisms of how eukaryotic enzymes can modify chromatin.

Moreover, these sequences act cooperatively in reporter gene constructs and recruit proteins that modify chromatin structure.

In keeping with this knowledge, it is important to note that hybridization and other stresses that lead to genome instability are also events that modify chromatin formatting.

HMGN1 protein binds to nucleosome and modifies chromatin structure.

These drugs, called epigenetic inhibitors, function to modify chromatin structure.