Sentence examples for modifying alleles for from inspiring English sources

Thus, quantitative modifying alleles for these traits are identified by low-resolution mapping followed by targeted sequence analysis to identify the causative mutation.

However, the nature of modifying alleles segregating in populations remains elusive for protein conformational diseases [ 15, 24].

Therefore, we now maintain a closed colony, C57BL/6JD- Apc Min (D for Dove), and monitor it regularly for tumor multiplicity to prevent introgression of modifying alleles that can arise through genetic drift in the B6 stock.

The striking phenotypic differences observed for each mutation may be due to differential genetic interactions with modifying alleles or cell-type dependent signaling interactions (i.e. endothelial vs. epithelial).

All affected and unaffected individuals were homozygous for the modified alleles.

But if thousands of alleles modify risk, for example, of schizophrenia – are they actually alleles 'for' this condition (Kendler 2005), or might they be better conceived as alleles 'for', say, the neurodevelopment of social cognition?

We measured the strength of LD using the Lewontin's normalised D' [ 59] modified for multiple alleles [ 60].

We were unable to either conditionally modify both alleles prior to embryonic day 8, or to generate germ-line transmission of deleted alleles.

Here we have extended this finding, showing that these modified Xist alleles are partially hypomethylated over the Xist promoter region, providing a mechanistic basis for preferential expression in XX heterozygotes.

The side chain structure of homomethionine-derived glucosinolates is modified by alleles at the AOP locus.

Since male animals have only one allele for the 533 markers on chromosome X, the procedure to estimate marker effects developed for markers with two alleles was modified for these SNP.