Sentence examples for modifying agents such from inspiring English sources

Early initiation of "disease modifying agents", such as beta interferon and glatiramer acetate appears to be of benefit in adults.

To enhance the success rate of filtration surgery, wound healing modifying agents, such as 5-fluorouracil or mitomycin C (MMC) are widely used [ 2- 7].

In this context, the combination of epigenetic modifying agents, such as azacitidine, lenalidomide and histone deacetylase inhibitors, with novel cellular therapy to include prophylactic DLIs, natural killer cell infusions, and leukemia-specific T cells or leukemia vaccines provides an exciting new avenue of research that may lead to improved treatment of leukemia relapse after allogeneic SCT.

Various molecules including epigenetic modifying agents such as HDACi, HMTi, and DNMTi have been shown to reactivate the virus in vitro, ex vivo, and in vivo.

Additionally, chromatin relaxation in the area surrounding DNA damage [ 77] potentiates the ATM signaling and radioresistance [ 78], as demonstrated by using histone deacetylase inhibitors and chromatin-modifying agents, such as chloroquine or osmotic shock [ 46].

Distinct irradiation schemes, chemotherapeutic drugs, HT and cell death-modifying agents such as zVAD-fmk bear high potential as immune-modulating agents besides their direct cytotoxic effects on the tumor cells.

In a preliminary study, our group showed, using isogenic cell populations expressing a fluorescent reporter, that modification of chromatin marks, using chromatin-modifying agents such as 5-azacytidine (5-AzaC) and trichostatin A (TSA), induced significant effects on mean fluorescence intensity (MFI) and normalized variance (NV; that is, the variance normalized by the square of the mean) [ 11].

Furthermore, in experiments using oxygen-modifying agents such as hydralazine, combretastatin or carbogen+nicotinamide, the change in the 3-h F-RI was shown to correlate very closely with changes in pO2 values determined using Eppendorf probes (Seddon et al, 2002).

The effect of the addition of structure-modifying agents such as ZnO on the processes of coke formation and sulphur poisoning of NiO/A12O3 catalyst during ethyne hydrogenation has been studied.

Based on their sensitivity to cleavage when intact nuclei are exposed to DNA-modifying agents, such as endonuclease DNase I, we can analyze the accessibility of the chromatin structure of specific genomic regions.

Alternatively, other bone-modifying agents such as calcitonin and PTH analogues are attracting increasing attention as potential DMOADs.