Sentence examples similar to modifying age from inspiring English sources

As diseases linked to aging can involve activation of p53-dependent changes in cellular protective pathways, the development of specific physiological models might further shed light on the role of p53 kinases in modifying age-related diseases.

Similarly we found no evidence that genotype modified age of cessation among former-smokers (data not shown).

Furthermore, we confirm that LTBP4 rs10880 modifies age at LoA in DMD.

SPP1 rs28357094 acts as a pharmacodynamic biomarker of GC response, and LTBP4 haplotype modifies age at LoA in the CINRG-DNHS cohort.

Moreover, polymorphisms in GST Omega-1 and -2 were shown to modify age at onset of PD (Li et al. 2006).

We show that polymorphic human prion protein gene codon 129 modifies age at onset: the earliest eight clinical onsets were all MM homozygotes and overall age at onset was 7 years earlier for MM compared with MV heterozygotes (P = 0.02).

For use as denominators in rate calculation, we obtained population data from age-, sex-, and race-specific population counts for census block groups from the modified age, race, sex, and Hispanic origin ("MARS") files from the 2000 US census.

For details see additional file 1. Original age sex index (ASIE+W) = Modified age sex index (ASIloc)† = † This formula was simplified from the published one: Please refer to additional file 1 for the reworking process.

However it remains unclear whether the MAPT gene also modified age of PD onset and whether there is a synergistic effect of both SNCA and MAPT on the age of onset of PD.

Perhaps the most clear-cut result with a profound impact on interpretation of HD pathogenesis is the demonstration that a functional polymorphism in the brain-derived neurotrophic factor (BNDF) gene does not modify age at neurologic onset [ 13- 16].

A slightly modified age-depth profile was developed for the 1998 ice core (DH-98-4) to account for the additional snow deposited between 1991 and 1998.