Sentence examples for modifying activity from inspiring English sources
PC exerts its disease modifying activity on OA, at least in part, by targeting immune system activation and the production of extracellular matrix and selecting chondroprotective proteins.
In view of the disease modifying activity of statins in two human immune-mediated diseases we initiated the DIATOR (Diabetes and Atorvastatin) Trial investigating the effects of treatment with atorvastatin in the course of recent-onset type 1 diabetes.
In the absence of ligand, interaction of the ligand-binding domain with corepressors such as NCoR1 or NCoR2/SMRT mediates transcriptional repression via recruitment of complexes with enzymatic histone modifying activity [5].
Because of its histone modifying activity and DNA-binding domains, it has been assumed that PRDM9 encodes a transcription factor that regulates other genes important for germ line meiosis but there is no direct evidence for such a role.
Differences in histone PTMs in cells treated with Dex±iAs could indicate an iAs effect on the histone itself or on a protein with histone modifying activity, such as a coactivator or corepressor.
Genistein possesses high histone modifying activity compared with other isoflavones, such as biochanin A and diadzein.
Which of the five His residues are critical for this taste-modifying activity?
These results indicate that the His residues of neoculin play an important role in its taste-modifying activity.
In this study, we found that not all five His residues of neoculin are necessary for its taste-modifying activity.
Neoculin is currently the only known protein that both tastes sweet and has a taste-modifying activity.
Neoculin variants with substitutions other than His-to-Ala were further analyzed to clarify the role of the NBS position 11 in the taste-modifying activity.
