Sentence examples for modify their microenvironment from inspiring English sources
Proteomic analysis in particular has enhanced understanding of how tumor cells modify their microenvironment through production of ECM structural proteins, ECM-modifying proteins and proteases.
Hypoxia causes cancer cells to modify their microenvironment by promoting angiogenesis.
These results demonstrate that 15-LOX-1 reexpression in colon cancer cells modulates cancer cells' ability to modify their microenvironment to promote angiogenesis and subsequently metastasis.
HCC cells were found to be modulated by the tumor milieu through the secretion of several factors, and the tumor cells modify their microenvironment in order to promote their own growth [ 16].
These studies are illustrative of the contribution of proteomic analysis to elucidating how tumor cells modify their microenvironment through the production of a diverse set of extracellular matrix proteins and proteases.
The induction of this form of cellular fate is biologically significant as senescent cells are able to modify their microenvironment by the secretion of transforming factors (Kuilman and Peeper, 2009; Young and Narita, 2009).
Tumor cells adapt to and modify their surrounding microenvironment [ 82].
In the present study, probably the effects of MSCs and rBMP-2 treated model culture Transwell, controlled environmental niches and alterations in this microenvironment can dramatically modify their behavior and differentiation capacities.
It is evident that the presence of myeloma cells in the bone marrow modulates the expression of cytokines from stromal cells, which enhances their ability to modify the microenvironment to support malignant growth.
These observations suggest that SDF-1α-loaded pH-sensitive polymeric micelles can be used as pH-triggered targeting agents and can effectively modify the microenvironment to increase innate neurorestorative processes.
In order to modify the microenvironment, FC-POP was covalently incorporated by various moieties to obtain a series of amine-functionalized FC-POPs (Scheme 1).
