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Several studies have been carried out to modify the sequence of GLP-1 in order to prevent degradation while conserving its valuable function.
The program does not modify the sequence of the images, except to invert the sequence if the first energies are in a decreasing order.
Genome editing with the CRISPR/Cas9 system is making it possible to modify the sequence of genes linked to these disorders.
Moreover, RNA editing can modify the sequence of miRNAs and the nCounter system would have not detected such editing events.
Future work is required to replace or modify the sequence of the signal peptide to enhance secretion and thus to increase extracellular activity.
In a gene conversion process a part or the whole sequence of one of the paralogous genes is used as a template to modify the sequence of another.
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Using analytical ultracentrifugation and NMR methods, we show here that a membrane-soluble peptide, MS1, designed by modifying the sequence of the water-soluble coiled-coil GCN4-P1, exhibits a reversible monomer-dimer-trimer association in detergent micelles with a greater degree of cooperativity in C14-betaine than in dodecyl phosphocholine detergents.
As a consequence, mutations occur with high frequency, thereby modifying the sequence of the HIV-1 proteins.
There is room for improvement by modifying the sequence of miRNAs or finding other sequences common to mRNAs or proteins of interest.
In general, the MESA platform enables design-based receptor engineering because it is possible to tune specific biophysical parameters by modifying the sequence of specific receptor domains.
Escherichia coli strain EL350 contains chromosomally integrated phage lambda Red recombinase genes enabling this strain to be used for modifying the sequence of resident clones via recombineering.
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