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Though there are few studies that evaluate the influence of anthropic changes on functional diversity under field conditions (most of the evidence comes from experiments carried out under controlled conditions), it has been proposed that human activities result in the loss or addition of species with certain functional traits and therefore modify the functioning of ecosystems [6].
The location of this LD block suggests that these variations somehow modify the functioning of FGFR2.
Studies have also shown that mutations in the hepatitis B X gene (HBx) protein modify the functioning of p53, a tumor suppressor gene [ 25].
In addition to the well-documented role that cytokines play in the immune response and inflammation [ 7, 8], cytokines also modify the functioning of epithelial cells.
Drugs can be designed to modify the functioning of the pathway in the diseased state by inhibiting a key molecule, or to enhance the normal pathway by promoting specific molecules that may have been affected in the diseased state.
Drugs can be designed to modify the functioning of the pathway in the diseased state by inhibiting a key molecule, or to enhance the normal pathway by promoting specific molecules that may have been affected in the diseased state and can influence the whole biological system by targets.
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The extensibility refers to the flexibility when the architecture is needed to append or modify the function modules.
Based on an approach in [8], the main idea in our considerations is to modify the functions.
Multi-target approaches are necessary to properly analyze or modify the function of a biochemical pathway or a protein family.
The signal passing through a neuron is transformed by weights which modify the functions and thus the output signal reaches the following neuron.
Curcumin has been shown to modify the function of membrane proteins by changing the lipid bilayer properties [52].
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