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CYP19A1 methylation also appeared to modify risk of early B2 associated with body weight.
Treatments that modify risk of death among those with diabetes may change future dementia risk.
This line of research suggests novel epigenetic mechanisms whereby diet may modify risk of human disease.
Polymorphisms in genes involved in all these processes may modify risk of developing idiosyncratic drug reactions.
Early life exposures may modify risk of inflammatory bowel diseases (IBD; Crohn's disease (CD), ulcerative colitis (UC)).
Exposure to pets, growing up on a farm, or daycare exposure did not modify risk of surgery in CD.
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For the analyses, we selected age ranges that we expected to be mostly free from knee and hip OA, allowing footwear to modify risks of incident OA rather than OA progression.
Our aim was to determine whether a change in fatty liver status (either development of new fatty liver, or resolution of existing fatty liver) over five years modified risk of incident hypertension at five year follow-up.
Established or suspected dietary factors modifying risk of CRC are red meat, cereals, fish, and fibre.
Our analysis also indicates the need for research to evaluate the role of CPAP in modifying risk of GDM (53).
Riboflavin, pyridoxine, folic acid, and vitamins A, C, and E significantly modified risk of arsenic-related skin lesions.
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