Sentence examples for modify organ function from inspiring English sources

Several epidemiological studies have suggested that environmental factors during the sensitive phases of development, especially the fetal period and infancy, modify organ function and may have life-long consequences on an individual's risk of several common adult diseases, including ischemic heart disease, type 2 diabetes, obesity, and osteoporosis [1] [3].

However, this benefit was associated with increased toxicity and has subsequently led to the recommendation to add docetaxel in patients with good KPS and organ function, using a modified regimen with either reduced dose, or as a weekly or biweekly regimen (Shah et al, 2010; Tebbutt et al, 2010; Van Cutsem et al, 2011b).

With the necessity of modifying dose based on age, weight, developmental status, organ function, drug interaction potential and other disease-modifying conditions looming, integrated solutions that synthesize this information should provide more informed decision making.

Key eligibility criteria included: age ≥ 70, diagnosis of advanced NSCLC (stage IIIB with pleural effusion or IV [ 17]); measurable disease according to modified RECIST criteria version 1.0 [ 18]; Eastern Cooperative Oncology Group performance status (ECOG-PS) 0 to 2; adequate organ function.

Using this approach, a typical CL (CLadult) for an adult weighing 70 kg is modified for size using allometry along with a maturation function (MF; between 0 and 1) to account for immaturity of CL processes and an organ function (OF; can be greater or less than 1) to account for disease modifications on CL.

A critical and deceptively simple benefit of these organs-on-a-chip is that they simulate, in a rudimentary way, the mechanical motion essential to organ function.

Sequential organ function assessment.

Physiological indices of organ function were recorded.

Thus, blocking iNOS may improve organ function.

To increase donor organ utilization, new donor management therapies are needed to optimize donor organ function.

No negative side effects on organ function were seen.