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However, GGTI-298 alone (10 µM) did not significantly modify expression of MHC-I and in particular HLA-A0201 (Figures 3A and 3B).

Temperature variation is one of the most commonly encountered environmental changes, and it has been reported that bacteria can modify expression of at least 10% of their genes in response to an increase or decrease in growth temperature [8], [9], [10].

Peroxisome proliferator activated receptors (PPARs) are steroid hormone nuclear receptors that modify expression of several genes.

We also studied whether CAP1/ Prss8 inactivation would modify expression of tight junction proteins.

Unfortunately, we showed that quercetin does not modify expression of TRAIL-R1 (Supplementary Figure S3).

Second, synthetic biologists can design new molecules to target and modify expression in a tightly controlled manner.

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William Jeffery and his colleagues have isolated a master control gene whose modified expression leads to blindness in cave fish (Yamamoto et al. 2004).

Signal transduction leads to modifying expression of defense-related genes and defense mechanisms against BPH, including sieve tube sealing, production of secondary metabolites, and induction of proteinase inhibitor.

Previous studies have shown that combination therapy modifies expression of hundreds of genes in vitro and in vivo.

Step 7: The DNA cassette was blunt-NotI ligated into an appropriately modified expression vector pSuper (Oligoengine).

From the results obtained, we sorted the genes exhibiting modified expression into five groups showed in Table S1.

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