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We developed a quantitative plate-based assay to identify siRNA duplexes that modify cellular responses to the Tumor Necrosis Factor-α (TNF) cytokine.
However, current models lack the relevant human physiological environment that might regulate or modify cellular responses (Pollard et al., 2008).
Glucocorticoids can modify cellular responses via genomic and non-genomic pathways, including regulation of ion transport processes [ 14- 17].
The ability of purified sulfolipids to modify cellular responses is well established [ 72, 73] but there are fewer reports of a direct role in virulence.
However, later studies showed that CCN proteins are matricellular proteins that modify cellular responses to extracellular factors via direct binding to cell surface receptors [ 5, 10– 10].
The mechanisms by which integrins modify cellular responses to growth factors can involve direct regulation of transcriptional programs, complex activation mechanisms or various signaling cascades.
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Despite exposing cells to a higher degree of stress, the minimal changes in cellular metabolism and cell proliferation we observed demonstrate that our combined stress protocol can modify cellular response without causing cytotoxic effects.
In summary, the results of this study indicateF-FDG PET scans may not be detrimental but can elicit variable responses between individuals and can modify cellular response to subsequent radiation exposures.
Metabolic stress changes cellular adenine nucleotide levels and resultantly modifies cellular response.
Matsudaira et al (1980) demonstrated with a 200 kVp polychromatic (p) X-rays tube that 5% of iodine in the cell growing medium modified cellular response to the irradiation, but no effect was shown with irradiation from Co.
By utilizing UDP-GlcNAc to modify cellular proteins, OGT may induce apoptosis in response to elevated flux through the hexosamine signaling pathway.
More suggestions(15)
modify inflammatory responses
modify cellular activities
modify physiological responses
modify immunological responses
modify transcriptional responses
modify cellular properties
modify immune responses
modify automatic responses
modify cellular functions
modify cytokine responses
modify cellular machines
modify cellular proteins
modify subject responses
modify spiking responses
modify Ca2+ responses
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